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TECHNOLOGY TRANSFER AT CRO AVIANO
 

FreccinaSpotlight
FreccinaTechnology Transfer Opportunities
FreccinaSpin-off companies
FreccinaFostering IP culture
 
Welcome to the National Cancer Institute - CRO Aviano Technology Transfer Office (TTO) webpage.
Our mission is to strengthen the economy from collaborations with private by moving results of translational research into societal use.
Feel free to send us licensing requests or partnership proposals (incl. project submissions to external funding agencies). A prompt answer and strict confidentiality will be assured in all cases.
 
Contact: Ermes Mestroni, Technology Transfer Manager and Grant Specialist
mail:
 
SPOTLIGHT
  1. CRO MEETS INDUSTRY 2012 exhibit was held on December 14th. Researchers, biotech companies, business and community leaders came together for a day of collaboration, bench-to-bedside creativity, and real-world novel applications. Programme.
    Right-click to download.
  1. STARTUP OPPORTUNITY @Pordenone Fiere. Two research groups from CRO Aviano translated life science innovation into professional business plans (Onco-Target and D4D) to join the brand new entrepreneurial competition (Punto di Incontro, 8-9 November 2012). Ready Chemio team delivered an Elevator Pitch.

  1. TR35-YOUNG INNOVATORS. Competition for the best ideas of applied research developed in Italy, with relevant potential for the creation of technology based companies. Awarded projects will be presented during the 2013 edition of the Research Innovation and Entrepreneurship Forum. Details.

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TECHNOLOGY TRANSFER OPPORTUNITIES
The following is a selection of the technologies available from CRO for commercial use and/or joint development. More technologies will be added in the near future.
Click titles for details and previews shareable on Facebook, Twitter,
LinkedIn, etc. (if you use Internet Explorer please scroll to top).
Right-click to download flyers.
 
  1. ACTION OF RETINOIC ACID ON CANCER CELLS ELUCIDATED
    Use of RA isomers in combination therapy for cancer and exploitation of cross-talk between significant pathways involved. Antiprolific properties in MCL cells.
  1. ANTITUMOR GOLD III COMPLEXES
    Innovative gold-peptido derivatives. Enormous potential as anticancer agents. Patent. National stage entry: China, Japan, Mexico, Canada, India, USA, Brazil.

  1. CRO BIOBANK
    Molecular targets and resources for prevention and personalization of medical treatment. A reference for the pharmaceutical industry.

  1. DIAGNOSTIC TOOLS IN ONCO-HEMATOLOGY
    Kits for an advanced assessment of genetic alterations and in vitro testing of putative drugs for CLL therapy.

  1. e-HEALTH DOMOTIC APPS
    Indoor navigation in complex confined environments.
    Tailored applications including interactive Patient Education contents.
  1. EPIGENETIC MARKERS OF PROGNOSIS AND RESPONSE TO THERAPY IN SOLID TUMORS
    Predictive markers of response to treatment. DNA methylation.
    Highly reliable and easily assessable prognostic tools. Patent, PCT extension.
  1. GENETIC AND GENOMIC TOOLS FOR THE DIAGNOSIS AND TREATMENT OF SOLID TUMORS
    Rapid, cost-effective assays for the identification of point mutations.
    Cancers of the colon-rectum, breast and ovary.

  1. hEMILIN1 antibody
    Expressed in smooth muscle and other mesenchymal tissues. ELISA detection, integrin interaction functional blocking, immunohistochemistry on frozen tissues, WB. TGF-β signaling inhibition.

  1. hEMILIN2 antibody
    MAb to ECM Elastin Microfibril Interface Located glycoproteIN.
    ELISA, immunoblot, facs assays. Regulation of extrinsec apoptotic pathway. Marker of hESC-derived cardiomyocytes.

  1. IDIOTYPIC VACCINES FOR IMMUNOTHERAPY OF B CELL LYMPHOMAS
    Shared idiotypic vaccines for “subset-specific” immunotherapy of B cell lymphoproliferative disorders (optimized to improve immunogenicity). Patents.
  1. IgM antibody anti HCV NS3 helicase region
    Hepatitis C Virus NS3 helicase, human IgG Fc region. Murine (IgM k).
    ELISA. Rheumatoid Factor activity.

  1. IORT-web
    Web based system designed for IORT procedures in radiotherapy department.

  1. mEMILIN1 antibody
    MAb that interacts with α4β1 integrin via C-terminal gC1q domain.
    Regulation of pro-TGF-β processing. Correct functioning of lymphatic vessels.

  1. miCRO RTPS - EQUIVALENT DOSE CALCULATOR IN RADIATION ONCOLOGY
    User-friendly calculator of biologically equivalent doses to the tumor and organs at risk in radiation oncology.

  1. MNEMO KAIROS Clinical Trials Software
    Database and applications that allow complete control over every aspect of clinical research studies. Integrated planning, reporting tools, financial information.

  1. Mobile QA
    Web based system designed for quality control procedures (radiotherapy, radiology, and nuclear medicine).

  1. MOLECULAR NANOTECHNOLOGY FOR HEALTH APPLICATIONS
    New platforms for tumor diagnostics, prognostics and treatment.
    Point-of-care-testing (POCT)- dedicated devices.

  1. MONOCLONAL ANTIBODY 213 anti BCR
    Human B Cell Receptor k light chain. Murine (IgG2b isotype). SH9 cell line or ScFv recombinant protein. Flow Cytometry, ELISA, Western Blot.
  1. MONOCLONAL ANTIBODY 215 anti BCR
    Human B Cell Receptor k light chain. Murine (IgG1 isotype). DG75 or SH9 cell line or recombinant protein. Flow Cytometry, ELISA, Western Blot.

  1. NOVEL PROGNOSTIC AND IMMUNOTHERAPEUTIC APPROACHES TO PATIENTS WITH SOLID TUMORS
    Laboratory development and clinical application of novel immunotherapeutic agents for the treatment of cancer patients.

  1. Patient Support Systems
    Tailored support systems for radiation therapy.

  1. PHARMACOGENETICS TOOLS FOR TAILORED THERAPIES
    Diagnostic devices and phase I-II clinical trials in the pharmacogenetics field.

  1. PSYCHO-ONCOLOGY CFSS
    Screening instruments for the self-assessment of cognitive deficit in oncological patients.

  1. READY CHEMIO
    Apparatus for the automatic preparation of a drug and respective method of preparation. European patent.

  1. SMART CLOT
    The most advanced technology for a more global assessment of haemostasis in whole blood, under flow conditions. Patents.

Click titles for details and previews shareable on Facebook, Twitter,
LinkedIn, etc. (if you use Internet Explorer please scroll to top).
Right-click to download flyers.

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SPIN-OFF COMPANIES
Start-up activity at CRO is key in promoting regional economic development.
It has raised more than 2 million euros since 2006.
The Technology Park of Pordenone hosts entrepreneurial initiatives based on CRO Aviano novel technologies.
 
PharmaDiagen
First Italian spin-off addressed to fight cancer through pharmacogenetics.
R&D intensive SME, PharmaDiagen S.r.l. produces devices predictive of response to antitumor drugs based on patients' individual genetic profile (pharmacogenetic Kits) and ICT-based tools with genetic information that help clinicians choose proper drugs and doses (pharmacogenetic Cards).
Unique example within Italy's National Health Service of a high-tech oriented company with an ownership share held by a public research organisation or hospital.
Winner of the 2009 START CUP business plan competition.
 
SediciDodici
Spin-off company founded by CRO researchers and local entrepreneurs to bring advanced technologies for the assessment of haemostasis on the market. Sedicidodici S.r.l. and the National Cancer Institute CRO Aviano signed an agreement to further develop the Smart Clot device. Patents in the field of diagnosis and pharmacological monitoring of thrombotic, ischemic and hemorragic pathology.
National Award of Innovation.
 
 
FOSTERING IP CULTURE
Our TTO is linked to innovation networks, marketplaces, and stakholders looking for new business opportunities. Special attention is devoted to education on Intellectual Property management and valorisation.
Click titles for details and previews shareable on Facebook, Twitter,
LinkedIn, etc. (if you use Internet Explorer please scroll to top).
Right-click to download flyers.
 
Cro Meets Industry
The first tech transfer showcase held at CRO Aviano on April 24th, 2009.
Info
 
In-House Training
  1. Technology Transfer: case studies, patenting in biomedicine and biotechnology.
    April 19th, 2011. Info
  1. Patents, spinoff companies, the CRO Portfolio of Ideas: instruments for new opportunities.
    April 30th, 2010. Info
  1. Problems and solutions in patenting biotech inventions in medical field. Creation of an IP market for biomed clusters.
    June 12th, 2008. Info
  1. Intellectual property protection.
    March 14th, 2007. Info